⸻ Programs & Pipeline
Four priority programs,
one integrated platform.
MACRO HRD concentrates on four priority programs actively advancing toward the clinic — supported by a broader set of enabling platforms and pipeline ventures that make each program possible.
★ · Focus
Priority Programs
The four programs we are actively advancing toward the clinic.
★ · Priority Program
HIV Functional Cure Program
An integrated therapeutic approach combining tri-specific antibodies, engineered immune effectors, and AI-guided coordination toward durable viral control.
★ · Priority Program
HPV Prevention Program
Immune-targeting therapeutic design for cervical cancer prevention, with mucosal delivery at the primary site of transmission.
★ · Priority Program
GBM Immunotherapy Program
An immune-based approach to glioblastoma engineered to cross the blood-brain barrier — advanced with a multi-institutional clinical network.
★ · Priority Program
TB Rapid Diagnostic
Next-generation tuberculosis diagnostic engineered for point-of-care deployment in high-burden regions.
01 · Foundation
Enabling Platforms
The scientific engines that power every priority program.
01 · Platforms
Multi-Specific Antibody Platform
Tri-specific antibody systems for precision targeting, immune recruitment, and viral escape prevention.
01 · Platforms
Engineered Immune Cells Platform
CAR-like NK systems and γδ T cell therapies for adaptive, MHC-independent elimination of diseased cells.
01 · Platforms
Functional Peptide Platform
A library of 20,000+ engineered peptides for membrane penetration, targeted delivery, and biological modulation.
01 · Platforms
GEDM-3DQ Decision Engine
Gradient Equilibrium Decision Modeling — the AI decision-intelligence layer behind every program.
01 · Platforms
Immune Cell Banking Platform
Pre-engineered, AI-preconditioned immune cell reserves — biological insurance for every client.
02 · Pipeline
Broader Pipeline
Additional programs developing behind the priority four.
02 · Infectious Disease
Pandemic Preparedness Platform
Antiviral therapeutic technologies and rapid-response treatment systems architected for the next unknown pathogen.
03 · Neuro & Oncology
Huntington's Disease Program
Precision neurotherapeutic strategies and molecular disease modeling for a monogenic disease with no current cure.
03 · Neuro & Oncology
Brain Mapping Platform
AI-assisted neuro-biomarker discovery through integrated proteomics and genomics.
03 · Neuro & Oncology
MSC Neuroregeneration Program
Mesenchymal stem cell therapies for neurodegenerative disease — secreted bioactive factors for repair.
03 · Infrastructure
Infrastructure
The foundation that makes translational medicine real at scale.
04 · Infrastructure
Ambient Cell Logistics
Room-temperature cell logistics — a bioinspired strategy that ends cold-chain dependency for cellular therapies.
04 · Infrastructure
GEDM-ICU
A research-grade, multimodal, trajectory-based intelligence layer deployed in critical-care settings.
04 · Infrastructure
SA Trial Hospital
A fast-track clinical trial hospital platform in South Africa for high-burden African diseases.
04 · Infrastructure
Lesotho SMPZ
A sovereign Special Medical Practice Zone concentrating regulatory authority, GMP, and biobanking in one jurisdiction.